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Publication year: 2009
Source: The American Journal of Cardiology, Volume 104, Issue 11, 1 December 2009, Pages 1465-1471
Kasper K., Iversen , Morten, Dalsgaard , Ane S., Teisner , Mikkel, Schoos , Borge, Teisner , …

To investigate whether pregnancy-associated plasma protein-A (PAPP-A) is a prognostic marker in patients admitted with high-risk acute coronary syndrome. In patients admitted with high-risk non–ST-segment elevation acute coronary syndrome (NSTE-ACS) and ST-segment elevation myocardial infarction (STEMI), risk stratification is primarily determined by the markers of myocardial necrosis and known demographic risk profiles. However, it has recently been proposed that the presence and extent of vulnerable plaques might influence the prognosis significantly. A marker for the vulnerable plaque could identify patients at high risk who would potentially benefit from intensive treatment and surveillance. Two populations of consecutive patients admitted with high-risk…

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