Smoking history and the incidence of age-related macular degeneration – Results from the Muenster Aging and Retina Study (MARS) cohort and systematic review of observational longitudinal studies
June 25th, 2009 Posted by: admin
Publication year: 2009
Source: Addictive Behaviors, In Press, Accepted Manuscript, Available online 27 May 2009
Bruno, Neuner , Alexander, Komm , Juergen, Wellmann , Martha, Dietzel , Daniel, Pauleikhoff , …
To compare the association of smoking with age-related macular degeneration (AMD) in the Muenster Aging and Retina Study (MARS) cohort with current evidence. Adjusted risk ratios for incident AMD in MARS were compared with findings of a systematic review and meta-analysis of observational prospective studies. 9.6% of MARS participants progressed to AMD over a median of 30.9 months. In MARS the adjusted risk ratio in current versus never smokers was 3.25 (95% confidence interval [1.50–7.06)]), and 1.28 [0.70–2.33] in former smokers versus never smokers. The meta-analysis of previous studies showed a pooled adjusted risk ratio of 2.51 [1.09 –5.76] in current…
