Significance of Postprandial Symptom Exacerbation in Hypertrophic Cardiomyopathy

February 16th, 2010    Posted by: admin

Publication year: 2010
Source: The American Journal of Cardiology, In Press, Corrected Proof, Available online 13 February 2010

Jonathon C., Adams , Steve R., Ommen , Kyle W., Klarich , A. Jamil, Tajik , Rick A., Nishimura

Patients with hypertrophic cardiomyopathy (HC) can experience exacerbation of exertional symptoms after a meal. The present study was designed to determine the prevalence and clinical correlates of postprandial symptom exacerbation (PPSE) in patients with HC. The records of 558 patients with HC and PPSE data who had undergone echocardiography at our institution from 2002 to 2006 were reviewed. Continuous-wave Doppler velocities were used to determine the left ventricular outflow tract gradient. Left ventricular filling was assessed using transmitral velocity curves. The Minnesota Living With Heart Failure questionnaire was administered to measure symptom limitations. A multivariate regression model was developed to…

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