Relation of Kidney Function and Albuminuria With Atrial Fibrillation (from the Heart and Soul Study)
Publication year: 2009
Source: The American Journal of Cardiology, Volume 104, Issue 11, 1 December 2009, Pages 1551-1555
David D., McManus , David C.M., Corteville , Michael G., Shlipak , Mary A., Whooley , Joachim H., Ix
Atrial fibrillation (AF) is common in end-stage renal disease, but the relation between more modest decrements in kidney function or albuminuria with AF is uncertain. Among 956 outpatients with coronary artery disease, kidney function was assessed using 3 methods (cystatin C–based estimated glomerular filtration rate [eGFRcys], creatinine-based eGFR [eGFRCr], and the urinary albumin/creatinine ratio [ACR]) and prevalent AF using surface electrocardiography. Multivariate logistic regression was used to evaluated the association of each measure of kidney function with AF. The mean eGFRcys was 71 ± 23 ml/min/1.73 m2, and the median ACR was 10 mg/g (interquartile range 6 to 19). Forty…