Relation Between Framingham Risk Categories and the Presence of Functionally Relevant Coronary Lesions as Determined on Multislice Computed Tomography and Stress Testing
Publication year: 2009
Source: The American Journal of Cardiology, In Press, Corrected Proof, Available online 21 July 2009
Gaetano, Nucifora , Joanne D., Schuijf , Jacob M., van Werkhoven , Roxana, Djaberi , Ernst E., van der Wall , …
Noninvasive assessment of subclinical atherosclerosis by multislice computed tomographic (MSCT) coronary angiography and demonstration of significant, flow-limiting coronary artery disease (CAD) by stress testing may improve patients’ risk stratification. However, data relating the complementary information provided by these noninvasive techniques to traditional risk assessment are scarce. In 255 subjects (45% women, mean age 54 ± 12 years) without known CAD, 64-slice MSCT coronary angiography and stress testing (exercise electrocardiographic test or myocardial perfusion imaging) were performed. Framingham risk score (FRS) was calculated from baseline characteristics (50% low, 22% intermediate, 28% high). Angiograms showing atherosclerosis were classified as obstructive (≥50% luminal…