Reasonable Duration of Clopidogrel Use After Drug-Eluting Stent Implantation in Korean Patients
Publication year: 2009
Source: The American Journal of Cardiology, Volume 104, Issue 12, 15 December 2009, Pages 1668-1673
Dong-Ho, Shin , In-Ho, Chae , Tae-Jin, Youn , Sung-Il, Cho , Dong-A., Kwon , …
Current guidelines recommend that clopidogrel be given to patients for 12 months after drug-eluting stent (DES) implantation. However, the evidence is insufficient to support the benefit of long-term clopidogrel therapy, especially in Asian patients. The aim of this study was to evaluate whether different durations of clopidogrel use might influence long-term outcomes after DES implantation. A total of 844 patients from 4 medical centers in Korea who had undergone successful DES implantation from November 2004 to April 2006 were enrolled. Patients who were event free at 6-month follow-up were divided into 2 groups by clopidogrel use (575 users, 163 nonusers)…