"iDoctor – Medical Blog"

Publication year: 2010
Source: The American Journal of Geriatric Pharmacotherapy, Volume 8, Issue 1, February 2010, Pages 73-76

Robi, Goswami , David, Van De Car , Kenneth E., Schmader , Thomas M., Bashore , Michael H., Sketch Jr

Background: Ranolazine is increasingly being prescribed for the treatment of chronic stable angina. This report describes an adverse effect that may be related to ranolazine.Case summary: A 77-year-old white man with chronic renal insufficiency was evaluated for moderate dyspnea on exertion (DOE). Cardiac and pulmonary workup revealed nonobstructive coronary artery disease and mild obstructive lung disease. The patient had been taking ranolazine 500 mg daily for possible angina for the past 2 months. Given the temporal association of his symptoms with drug initiation, ranolazine was discontinued during the hospitalization. One month after discontinuing ranolazine, the patient’s DOE had completely resolved;…

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