Prevalence of Aspirin and Clopidogrel Resistance Among Patients With and Without Drug-Eluting Stent Thrombosis
Publication year: 2009<br><b>Source:</b> The American Journal of Cardiology, Volume 104, Issue 4, 15 August 2009, Pages 525-530<br>Tina L., Pinto Slottow , Laurent, Bonello , Rekha, Gavini , Patricia, Beauzile , Steven J., Sushinsky , …<br><br>Drug-eluting stent (DES) thrombosis has a multifactorial etiology. Variable responsiveness to antiplatelet therapy likely contributes to its pathogenesis. We aimed to determine whether patients who had experienced DES thrombosis compared with a cohort of patients who had not would exhibit greater platelet reactivity and a greater prevalence of aspirin and clopidogrel resistance. The effect of aspirin and clopidogrel on platelet reactivity was determined after angiographically proven DES thrombosis in 26 patients and in 21 patients