Peripheral Vascular Endothelial Function in Patients With Hypertrophic Cardiomyopathy
December 19th, 2009 Posted by: admin
Publication year: 2010
Source: The American Journal of Cardiology, Volume 105, Issue 1, 1 January 2010, Pages 112-115
Kevin S., Heffernan , Craig A., Napolitano , Martin S., Maron , Eshan A., Patvardhan , Ayan R., Patel , …
Patients with hypertrophic cardiomyopathy (HC) have coronary microvascular dysfunction, which is an independent predictor of adverse left ventricular remodeling, systolic dysfunction, and mortality in these patients. Whether these defects in vasomotor function are localized to the coronary arteries or whether systemic vasomotor dysfunction is present in patients with HC has not yet been adequately examined. The aim of this study was to test the hypothesis that patients with HC have altered peripheral vascular endothelial function. Subjects without coronary artery disease (CAD) and those with CAD served as negative and positive controls, respectively. Conduit artery endothelium-dependent vasomotion was assessed with ultrasound…
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