Optimal Medical Therapy With or Without Percutaneous Coronary Intervention for Patients With Stable Coronary Artery Disease and Chronic Kidney Disease
December 7th, 2009 Posted by: admin
Publication year: 2009
Source: The American Journal of Cardiology, Volume 104, Issue 12, 15 December 2009, Pages 1647-1653
Steven P., Sedlis , Claudine T., Jurkovitz , Pamela M., Hartigan , David S., Goldfarb , Jeffrey D., Lorin , …
Chronic kidney disease (CKD) is a risk factor for poor outcomes in patients with coronary artery disease (CAD), but it is unknown whether CKD influences the efficacy of alternative CAD treatment strategies. Thus, we compared outcomes in stable CAD patients with and without CKD randomized to percutaneous coronary intervention (PCI) and optimal medical therapy (OMT) or OMT alone in a post hoc analysis of the 2,287 patient COURAGE study. At baseline, 320 patients (14%) had CKD defined as a glomerular filtration rate of <60 mL/min/1.73 m2, as estimated by the abbreviated 4-variable Modification of Diet in Renal Disease equation. The…
