N-Terminal Pro–Brain Natriuretic Peptide and Outcomes in Patients Undergoing Surgical Ventricular Restoration
Publication year: 2010
Source: The American Journal of Cardiology, Volume 105, Issue 5, 1 March 2010, Pages 640-644
Andrea, Ballotta , Marco, Ranucci , Alessia, Kunkl , Hisham, El Baghdady , Eduardo, Bossone , …
N-terminal pro–brain natriuretic peptide (NT–pro-BNP) levels have been shown to be increased at baseline in patients undergoing surgical ventricular restoration (SVR) of the left ventricle. However, changes in the values of this marker in the early postoperative period and its prognostic significance remain less known in these patients. We evaluated 31 consecutive patients undergoing SVR who had NT–pro-BNP determined a day before SVR and from postoperative days 0 to 4. Major morbidity was defined as ≥1 of the following: ventilation >48 hours, stroke, acute renal failure, low cardiac output, reoperation, or mediastinitis. The association of preoperative NT–pro-BNP with perioperative outcomes…