Major Adverse Cardiac Events in Patients With Moderate to Severe Renal Insufficiency Treated With First-Generation Drug-Eluting Stents

December 23rd, 2009    Posted by: admin

Publication year: 2009
Source: The American Journal of Cardiology, In Press, Corrected Proof, Available online 22 December 2009
Rishi, Sukhija , Wilbert S., Aronow , Chandrasekar, Palaniswamy , Tarunjit, Singh , Rashmi, Sukhija , …

No data are available comparing the long-term outcome of sirolimus-eluting stents (SESs) versus paclitaxel-eluting stents (PESs) in patients with moderate to severe renal insufficiency. The incidence of major adverse cardiac events (MACE), including death, myocardial infarction, and target vessel revascularization, during long-term follow-up were studied in patients with a glomerular filtration rate of <60 ml/min/1.73 m2, as measured by the Modification of Diet in Renal Disease (MDRD) study equation, who also underwent percutaneous coronary intervention with drug-eluting stents. Of 428 patients studied, PESs were placed in 287 patients and SESs in 141 patients. Stepwise Cox regression analyses were performed to…

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