Incidence and Progression of Aortic Valve Calcium in the Multi-Ethnic Study of Atherosclerosis (MESA)
February 25th, 2010 Posted by: admin
Publication year: 2010
Source: The American Journal of Cardiology, Volume 105, Issue 5, 1 March 2010, Pages 701-708
David S., Owens , Ronit, Katz , Junichiro, Takasu , Richard, Kronmal , Matthew J., Budoff , …
Aortic valve calcium (AVC) is common among older adults and shares epidemiologic and histopathologic similarities to atherosclerosis. However, prospective studies have failed to identify meaningful risk associations with incident (“new”) AVC or its progression. In the present study, AVC was quantified from serial computed tomographic images from 5,880 participants (aged 45 to 84 years) in the Multi-Ethnic Study of Atherosclerosis, using the Agatston method. Multivariate backward selection modeling was used to identify the risk factors for incident AVC and AVC progression. During a mean follow-up of 2.4 ± 0.9 years, 210 subjects (4.1%) developed incident AVC. The incidence rate (mean…
