Implication of the Continuous Prognostic Spectrum of Doppler Echocardiographic Derived Coronary Flow Reserve on Left Anterior Descending Artery

December 9th, 2009    Posted by: admin

Publication year: 2009
Source: The American Journal of Cardiology, In Press, Corrected Proof, Available online 3 December 2009
Lauro, Cortigiani , Fausto, Rigo , Sonia, Gherardi , Francesco, Bovenzi , Eugenio, Picano , …

The additive prognostic value of coronary flow reserve (CFR) over regional wall motion has been established, but there is more than a binary (normal–abnormal) response in CFR, which can be continuously titrated. We assessed the prognostic value of quartiles of CFR, evaluated by transthoracic Doppler of the left anterior descending coronary artery (LAD), in patients with known or suspected coronary artery disease (CAD). One thousand six hundred twenty patients (1,006 men, 64 ± 11 years of age) underwent dipyridamole (up to 0.84 mg/kg over 6 minutes) stress echocardiography with CFR evaluation of LAD by Doppler and coronary angiography. Patients were…

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