Efficacy and safety profile of a single dose of hydromorphone compared with morphine in older adults with acute, severe pain: A prospective, randomized, double-blind clinical trial
Publication year: 2009
Source: The American Journal of Geriatric Pharmacotherapy, Volume 7, Issue 1, February 2009, Pages 1-10
Andrew K., Chang , Polly E., Bijur , Angelo, Baccelieri , E. John, Gallagher
Background: Older adults (ie, those aged ≥65 years) are the fastest growing segment of the US population, with an estimated ~71 million expected by 2030. Over the past 10 years, there has been an 11% increase in the number of emergency department (ED) visits by older adults, and pain is their most common chief complaint.Objective: The goal of this study was to compare weight-based IV hydromorphone and IV morphine in adults aged ≥65 years presenting to the ED with acute, severe pain.Methods: This was a prospective, randomized, double-blind clinical trial of older adults with acute, severe pain at an adult,…