Effect of Sinus Rhythm Restoration After Electrical Cardioversion on Apelin and Brain Natriuretic Peptide Prohormone Levels in Patients With Persistent Atrial Fibrillation
December 19th, 2009 Posted by: admin
Publication year: 2010
Source: The American Journal of Cardiology, Volume 105, Issue 1, 1 January 2010, Pages 90-94
Eleftherios M., Kallergis , Emmanuel G., Manios , Emmanuel M., Kanoupakis , Hercules E., Mavrakis , Christos A., Goudis , …
Because humoral alterations have been implicated in the generation and perpetuation of atrial fibrillation (AF), we aimed to elucidate possible abnormalities in atrial endocrine function in the setting of lone AF. Levels of plasma apelin and amino terminal fragment of the brain natriuretic peptide prohormone (NT–pro-BNP) were measured in 40 patients with persistent AF, before and 1 month after electrical cardioversion, and in 15 controls in sinus rhythm (SR). All patients were successfully cardioverted to SR, although in 9 of them AF recurred. Baseline apelin levels were lower and NT–pro-BNP levels higher in patients with AF compared to controls (380…
