Effect of Quinapril on In-Stent Restenosis and Relation to Plasma Apoptosis Signaling Molecules
November 15th, 2009 Posted by: admin
Publication year: 2009<br><b>Source:</b> The American Journal of Cardiology, In Press, Corrected Proof, Available online 14 November 2009<br>Spyridon, Deftereos , Georgios, Giannopoulos , Charalampos, Kossyvakis , Andreas, Kaoukis , Konstantin, Raisakis , …<br><br>Angiotensin-converting enzyme inhibitors have been reported to inhibit in-stent restenosis. To assess the effect of angiotensin-converting enzyme inhibition on in-stent restenosis and its relation to apoptosis, 86 patients with chronic coronary artery disease who required stent implantation in the left anterior descending coronary artery or a major diagonal branch were studied. Patients were randomized to receive quinapril 40 mg/day orally (n = 43) or a placebo (n = 43). Drug therapy was initiated 1 week before initial
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