Effect of Narcotic Treatment on Outcomes of Acute Coronary Syndromes
Publication year: 2010
Source: The American Journal of Cardiology, In Press, Corrected Proof, Available online 13 February 2010
Zaza, Iakobishvili , Avital, Porter , Alexander, Battler , Solomon, Behar , Arie, Roth , …
Current guidelines have recommended intravenous narcotics (IVNs) for patients with ST-segment elevation acute coronary syndromes (STEACS) and patients with non-STEACS (NSTEACS), although the safety of IVNs has been challenged. We performed a retrospective analysis of the 30-day outcomes stratified by IVN use among patients enrolled in a national survey, using logistic regression and propensity score analysis. Of the 765 patients with STEACS and 993 patients with NSTEACS, 261 (34.1%) and 97 (9.8%) had received IVNs, respectively. The patients with STEACS who received IVNs were more likely to undergo reperfusion (79.7% vs 55.2%, p <0.0001), received it more rapidly (median 59…