Effect of Chronic Beta-Blocker Use on Stroke After Noncardiac Surgery
June 27th, 2009 Posted by: admin
Publication year: 2009
Source: The American Journal of Cardiology, In Press, Corrected Proof, Available online 8 June 2009
Felix, van Lier , Olaf, Schouten , Ron T., van Domburg , Patrick J., van der Geest , Eric, Boersma , …
The incidence of postoperative stroke ranges from 0.08% to 0.7% in noncardiac surgery. Recently, the PeriOperative ISchemic Evaluation (POISE) study reported an incidence of postoperative stroke of 1% in patients scheduled for noncardiac surgery when β blockers were initiated immediately before surgery. To assess the association between chronic β-blocker use and postoperative stroke in noncardiac surgery, we undertook a case-control study among 186,779 patients who underwent noncardiac surgery from 2000 to 2008 at the Erasmus Medical Centre. Patients who were undergoing intracerebral surgery or carotid surgery or who had head and/or carotid trauma were excluded. The case subjects were 34…
