Effect of Chronic Aspirin Therapy on Angiographic Thrombotic Burden in Patients Admitted for a First ST-Elevation Myocardial Infarction
January 23rd, 2010 Posted by: admin
Publication year: 2010
Source: The American Journal of Cardiology, In Press, Corrected Proof, Available online 22 January 2010
Giampaolo, Niccoli , Cristina, Spaziani , Marcello, Marino , Maria Luisa, Pontecorvo , Nicola, Cosentino , …
Myocardial no-reflow may negate the benefit of urgent coronary revascularization in patients with acute ST-elevation myocardial infarction (STEMI). Among its pathogenetic mechanisms, distal embolization is of prominent importance and several studies have shown that a high coronary thrombotic burden is associated with distal embolization. We aimed at assessing predictors of angiographic thrombus grade in patients undergoing primary percutaneous coronary intervention. Ninety-one patients (62 ± 12 years old, 79% men) presenting for a first STEMI and undergoing urgent coronary angiography within 12 hours from onset of symptoms were consecutively included in the study. Thrombus grade was evaluated by angiography according to…
