Does use of antihypertensive drugs affect the incidence or progression of dementia? A systematic review
November 30th, 2009 Posted by: admin
Publication year: 2009
Source: The American Journal of Geriatric Pharmacotherapy, Volume 7, Issue 5, October 2009, Pages 250-261
Kairav, Shah , Salah U., Qureshi , Michael, Johnson , Niraj, Parikh , Paul E., Schulz , …
Background: Hypertension appears to contribute to the development of dementia. Antihypertensive drugs may play an important role in altering the incidence or progression of dementia, particularly dementia of the vascular type; however, the neuroprotective effects of these agents in other types of dementia are not well characterized.Objectives: The main aims of this review were to examine the relationship between use of antihypertensive agents and the incidence and progression of Alzheimer’s dementia (AD), vascular dementia (VaD), and unspecified dementia, and to consider whether these agents may be neuroprotective.Methods: A search of the English-language literature (January 1996–August 2009) was conducted using PubMed,…
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