Cross-Sectional Relations of Lipid Concentrations to Left Ventricular Structural Attributes

March 13th, 2010    Posted by: admin

Publication year: 2010
Source: The American Journal of Cardiology, In Press, Corrected Proof, Available online 11 March 2010

Raghava S., Velagaleti , Michael J., Pencina , Ramachandran S., Vasan , Emelia J., Benjamin , Joseph M., Massaro , …

Although previous investigations reported on the associations of lipid concentrations with left ventricular remodeling in specific subpopulations, few data exist on these associations in a community-based sample of subjects without cardiovascular disease. In this study, 3,554 Framingham Heart Study participants (mean age 47 years, 53% women) without preexisting clinical cardiovascular disease were examined, and no meaningful associations of high-density lipoprotein cholesterol or non–high-density lipoprotein cholesterol with echocardiographic indexes of left ventricular structure were observed. In conclusion, these data do not support an independent association between lipid concentrations and left ventricular structure.

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