Comparison of Prognostic Value of Tissue Doppler Imaging in Carcinoid Heart Disease Versus the Value in Patients With the Carcinoid Syndrome but Without Carcinoid Heart Disease
Publication year: 2010
Source: The American Journal of Cardiology, Volume 105, Issue 4, 15 February 2010, Pages 527-531
Nicolas, Mansencal , William J., McKenna , Emmanuel, Mitry , Alain, Beauchet , Denis, Pellerin , …
The aim of this study was to evaluate the prognostic value of tissue Doppler imaging (TDI) in carcinoid heart disease (CHD). We prospectively enrolled 56 consecutive patients with proved digestive endocrine tumor and carcinoid syndrome. All patients underwent serial conventional, contrast, and TDI echocardiographic studies. The end point was all-cause mortality. Mean follow-up was 34 ± 21 months. At the end of follow-up, 30 patients (54%) presented right CHD and 13 patients (23%) left CHD. A progression of CHD was documented in 23 patients (41%). Twenty-two patients (39%) died during follow-up. According to mortality receiver operating characteristic curves, ratio of…