"iDoctor – Medical Blog"

Publication year: 2009
Source: The American Journal of Cardiology, In Press, Corrected Proof, Available online 18 July 2009
Tomonori, Okamura , Akira, Sekikawa , Takashi, Kadowaki , Aiman, El-Saed , Robert D., Abbott , …

The relation between cholesteryl ester transfer protein (CETP) levels and atherosclerosis is controversial. We examined whether the serum CETP levels were associated with subclinical atherosclerosis, independent of its most common gene variant, in a sample of Japanese men. A population-based cross-sectional study of 250 Japanese men aged 40 to 49 years was conducted to assess the intima-media thickness of the carotid artery, coronary artery calcium, serum CETP levels, and the CETP D442G gene variant. Compared with the lowest CETP quartile, the multivariate adjusted odds ratio for coronary artery calcium was 0.77 (95% confidence interval 0.18 to 3.36), 0.96 (95% confidence…

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