Calcium Metabolism in Adults With Severe Aortic Valve Stenosis and Preserved Renal Function
February 7th, 2010 Posted by: admin
Publication year: 2010
Source: The American Journal of Cardiology, In Press, Corrected Proof, Available online 5 February 2010
Kemal, Akat , Jens Johannes, Kaden , Fabian, Schmitz , Silke, Ewering , Anja, Anton , …
Data suggest a link of aortic stenosis (AS) with calcium and bone metabolism. To further investigate this, the following parameters were analyzed in 38 patients with severe AS and in 38 age- and gender-matched controls, without obstructive coronary artery disease and with preserved renal function: calcium, phosphate, 1,25(OH2)-vitamin D3, intact parathyroid hormone (iPTH), and osteoprotegerin. Patients with AS had significantly higher serum levels of calcium (2.63 ± 0.28 vs 2.48 ± 0.23 mmol/L, p <0.01) and phosphate (1.56 ± 0.33 vs 1.38 ± 0.26 mmol/L, p <0.01) and increased calcium-phosphorus products (4.16 ± 1.13 vs 3.44 ± 0.89 mmol/L2, p…
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