Baseline Low-Density Lipoprotein Cholesterol Levels and Outcome in Patients With Heart Failure
Publication year: 2010
Source: The American Journal of Cardiology, Volume 105, Issue 1, 1 January 2010, Pages 100-104
Gideon, Charach , Jacob, George , Arie, Roth , Ori, Rogowski , Dov, Wexler , …
The incidence of heart failure (HF) is constantly increasing in the Western world. Treatment with statins is well established for the primary and secondary prevention of cardiac events by lowering low-density lipoprotein (LDL) cholesterol levels. There are conflicting reports on the role of LDL cholesterol as an adverse prognostic predictor in patients with advanced HF. The aim of this study was to investigate the association between LDL cholesterol levels and clinical outcomes in 297 patients with severe HF (average New York Heart Association class 2.8). The mean follow-up period was 3.7 years (range 8 months to 11.5 years), and 37%…