Publication year: 2010
Source: The American Journal of Geriatric Pharmacotherapy, Volume 8, Issue 4, August 2010, Pages 294-315
Lindy D., Wood , Joshua J., Neumiller , Stephen M., Setter , Erin K., Dobbins
Background: Parkinson’s disease (PD) is associated with a host of nonmotor symptoms, including psychosis, cognitive impairment, depression, sleep disturbance, swallowing disorders, gastrointestinal symptoms, and autonomic dysfunction. The nonmotor symptoms of PD have the potential to be more debilitating than the motor features of the disorder.Objective: The aim of this article was to review treatment options for the nonmotor manifestations of PD, including pharmacologic and nonpharmacologic interventions.Methods: The PubMed and MEDLINE databases were searched for articles published in English between January 1966 and April 2010, using the terms Parkinson’s disease, nonmotor, psychosis, hallucination, antipsychotic, cognitive impairment, dementia, depression, sleep disturbance, sleepiness,…